Welcome to ASA-View:
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This server provides graphical representation of solvent accessibility of amino acid residues in
proteins, with known structures.
Proteins structures have been taken from the Protein Data Bank and DSSP program was used
to compute their solvent accessibility. Absolute surface area (ASA) of each residue provided by
DSSP
was transformed to relative values of ASA. Two types of plots are provided here.
First plot, called Spiral Plot is a new method to quickly notice the surface residues in a
protein. These may be the residues of interest. These spiral plots are generated by sorting all
residues by their relative solvent accessibility. The radius of the sphere representing each residue
is proportional to the accessible surface area of that residue, thus enabling a visual estimate of
more accessible residues. These residues are then arranged in form of a spiral, such that the inner
residues in this spiral represent buried residues and more and more exposed residues come nearer to
the outer ring of the spiral. Spiral plots are followed by Bar plots. These Bar Plots display solvent accessibility of amino acid residues in form of bar charts. Residues are arranged in the order they appear in the original structure. Graphics in Acrobat PDF format and PNG image format are provided. They can be downloaded or viewed online. |