Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -1 -2 -3 -1 0 -2 -3 -2 1 2 -1 5 0 -2 -1 -1 -1 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 2 A 4 -1 -2 -2 0 -1 -1 0 -2 -1 -1 -1 -1 -2 -1 1 0 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 3 S 1 -1 1 0 -1 0 0 0 -1 -2 -2 0 -1 -2 -1 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 4 N -2 -1 7 1 -3 0 -1 -1 0 -4 -4 0 -3 -3 -2 0 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.88 0.08 5 E 2 3 -1 -1 -2 1 3 -1 -1 -3 -2 1 -2 -3 -2 0 -1 -3 -2 -2 40 30 0 0 0 0 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0.37 0.08 6 A 4 -1 -1 -1 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 3 0 -3 -2 -1 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 0 0 0.43 0.08 7 R 2 3 -1 -2 -2 3 0 -1 -1 -3 -2 1 -1 -3 -2 0 -1 -3 -2 -2 40 30 0 0 0 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.38 0.08 8 Y -2 -2 -2 -4 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.05 0.08 9 V -1 -2 -2 -1 -2 0 3 -3 -2 1 0 -1 0 -2 -2 -1 -1 -3 -2 3 0 0 0 0 0 0 40 0 0 0 0 0 0 0 0 0 0 0 0 60 0.30 0.08 10 L -2 -3 -4 -4 -2 -3 -4 -4 -4 3 4 -3 1 0 -3 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 27 73 0 0 0 0 0 0 0 0 0 0.58 0.16 11 A 3 -3 -3 -3 -1 -2 -3 -2 -3 3 2 -2 0 -1 -2 -1 -1 -3 -2 1 40 0 0 0 0 0 0 0 0 27 32 0 0 0 0 0 0 0 0 0 0.31 0.16 12 E -1 1 -1 0 -4 1 4 -2 -1 -4 -3 5 -2 -4 -2 -1 -1 -4 -2 -3 0 0 0 0 0 0 40 0 0 0 0 60 0 0 0 0 0 0 0 0 0.66 0.16 13 E -1 0 -1 1 -4 4 5 -3 0 -4 -3 1 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 27 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.16 14 V -2 -3 -3 -4 -2 -3 -3 -4 -1 1 0 -3 0 4 -3 -2 -1 0 5 3 0 0 0 0 0 0 0 0 0 0 0 0 0 27 0 0 0 0 32 40 0.55 0.16 15 D -1 -2 0 4 -2 -1 0 -2 -2 -3 -3 -1 -2 -3 -2 2 3 -4 -3 -2 0 0 0 40 0 0 0 0 0 0 0 0 0 0 0 27 32 0 0 0 0.53 0.16 16 F -3 -3 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 0 7 -4 -3 -3 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.08 0.16 17 S -1 -2 1 5 -3 -1 1 -1 -2 -3 -4 -1 -3 -4 -2 3 0 -4 -3 -3 0 0 0 60 0 0 0 0 0 0 0 0 0 0 0 40 0 0 0 0 0.72 0.16 18 S 0 3 0 -1 -1 0 0 -1 -1 -2 -2 0 -1 -2 -1 3 0 -2 -1 -2 3 22 1 2 1 1 2 2 1 2 3 2 1 1 2 50 2 0 1 2 0.28 0.11 19 P 0 -1 -1 -1 -1 0 0 -1 -1 -1 -1 0 -1 -1 6 0 0 -1 -1 -1 5 3 3 3 1 3 4 4 1 3 5 3 1 2 43 4 3 1 2 4 0.60 0.06 20 E -1 0 0 1 -3 1 5 -2 0 -2 -2 0 -2 -2 -1 0 -1 -2 -2 -2 2 1 1 1 1 1 75 2 1 1 2 2 1 1 1 2 2 0 1 2 0.59 0.11 21 E -1 -2 0 4 -4 0 4 3 -1 -4 -4 -1 -3 -4 -2 -1 -2 -4 -3 -3 0 0 0 27 0 0 40 32 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.16 22 V -1 -3 -3 -4 -2 -2 -3 -4 -3 4 1 -3 4 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 32 0 0 27 0 0 0 0 0 0 40 0.47 0.16 23 K -1 1 3 0 -4 1 3 -2 -1 -4 -3 4 -2 -4 -2 0 -1 -4 -3 -3 0 0 27 0 0 0 32 0 0 0 0 40 0 0 0 0 0 0 0 0 0.56 0.16 24 N -1 -1 6 0 -3 -1 -1 3 0 -4 -4 -1 -3 -4 -3 0 -1 -4 -3 -4 0 0 68 0 0 0 0 32 0 0 0 0 0 0 0 0 0 0 0 0 0.80 0.16 25 W -2 -3 -4 -4 -2 -3 -3 -4 -3 3 0 -3 0 0 -4 -3 -2 9 0 3 0 0 0 0 0 0 0 0 0 32 0 0 0 0 0 0 0 40 0 27 0.98 0.16 26 W -3 -2 -3 -3 -3 3 -1 -3 -1 -2 -2 -2 -1 4 -4 -2 -2 8 4 -2 0 0 0 0 0 25 0 0 0 0 0 0 0 24 0 0 0 30 20 0 0.97 0.22 27 N 1 -1 6 0 -3 -1 -1 -1 0 -4 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 20 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.22 28 S -1 0 4 3 -3 0 0 -1 -1 -4 -4 2 -3 -4 -2 3 0 -4 -3 -3 0 0 25 20 0 0 0 0 0 0 0 24 0 0 0 30 0 0 0 0 0.50 0.22 29 G -1 -1 -1 -2 -3 -1 -2 6 -2 -4 -4 2 -3 -4 -3 -1 -2 -3 -3 -4 0 0 0 0 0 0 0 76 0 0 0 24 0 0 0 0 0 0 0 0 0.96 0.22 30 T -1 -2 -1 -2 -2 -1 -2 -2 -2 -1 -2 -1 -1 -3 -2 1 6 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.83 0.22 31 W -3 -1 -3 -3 -3 -1 -2 -3 -1 -3 -2 2 -2 1 -3 -2 -2 10 5 -3 0 0 0 0 0 0 0 0 0 0 0 24 0 0 0 0 0 51 25 0 1.39 0.22 32 Q -1 -1 -1 -1 -3 5 0 -2 -1 -3 -3 0 -2 -4 4 2 -1 -3 -3 -3 0 0 0 0 0 51 0 0 0 0 0 0 0 0 25 24 0 0 0 0 0.75 0.22 33 A 3 -2 -1 3 -2 -2 -1 -1 -2 -1 1 -2 -1 -2 -2 0 -1 -3 -3 -1 51 0 0 25 0 0 0 0 0 0 24 0 0 0 0 0 0 0 0 0 0.35 0.22 34 E -1 -1 3 0 -3 1 4 -2 -1 -3 -3 0 -2 -4 -2 0 3 -4 -3 -2 0 0 20 0 0 0 54 0 0 0 0 0 0 0 0 0 25 0 0 0 0.61 0.22 35 F -3 -3 -4 -4 -3 -3 -4 -4 -1 2 0 -3 0 6 -4 -3 -2 0 5 0 0 0 0 0 0 0 0 0 0 25 0 0 0 51 0 0 0 0 24 0 0.76 0.22 36 G -1 -1 -1 0 -3 0 3 4 -1 -3 -3 2 -2 -3 -1 -1 -1 -2 -2 -2 2 1 1 1 0 1 27 37 1 1 2 17 1 1 1 2 1 0 1 2 0.40 0.17 37 S 0 -2 -1 -2 -2 -1 -2 -2 -2 1 -2 -1 -1 -3 -2 4 4 -4 -2 -1 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 49 34 0 0 0 0.49 0.27 38 P -1 -1 -1 -1 -3 4 0 -2 -1 -3 -2 0 -2 -3 6 -1 -1 -2 -2 -2 2 1 1 1 0 38 1 2 0 1 2 1 0 1 43 2 1 0 1 1 0.89 0.21 39 D 1 -2 0 6 -3 -1 0 -2 -2 -3 -4 -1 -3 -4 -2 2 -1 -5 -3 -3 17 0 0 62 0 0 0 0 0 0 0 0 0 0 0 21 0 0 0 0 0.77 0.27 40 I -2 -4 -4 -4 -2 -4 -4 -5 -3 4 3 -4 1 4 -4 -3 -2 -2 0 1 0 0 0 0 0 0 0 0 0 42 37 0 0 21 0 0 0 0 0 0 0.60 0.27 41 E -1 0 -1 0 -4 3 4 -2 -1 -4 -3 2 -2 -4 -2 2 -1 -4 -3 -3 0 0 0 0 0 19 46 0 0 0 0 18 0 0 0 17 0 0 0 0 0.64 0.27 42 W -2 4 -1 -2 -3 0 -1 -2 5 -3 -2 0 -2 -1 -2 -2 -2 8 0 -3 1 38 1 1 0 1 1 1 22 1 2 1 0 1 1 1 1 25 1 1 0.81 0.22 43 N -1 -1 4 -1 -2 3 0 -1 -1 -3 -3 0 -2 -3 4 2 -1 -3 -2 -2 1 1 25 1 0 22 1 1 0 1 2 1 0 1 20 19 1 0 1 1 0.49 0.22 44 G -1 -2 -1 -2 -2 -2 -2 5 -2 -1 -2 -2 -2 -2 -2 -1 -1 -3 -3 2 1 1 1 1 0 1 1 63 0 1 2 1 0 1 1 1 1 0 1 22 0.65 0.22 45 E -2 -2 4 0 -3 -1 3 -2 -1 -2 1 -1 -1 -3 -3 -1 2 -4 -3 -2 0 0 37 0 0 0 25 0 0 0 21 0 0 0 0 0 17 0 0 0 0.42 0.27 46 V -1 -1 3 -1 -2 -1 -1 -2 -1 -1 -2 2 -1 -2 3 -1 -1 -3 -2 2 1 1 22 1 0 1 1 1 0 1 2 20 0 1 18 1 1 0 1 26 0.32 0.22 47 G -1 -1 -1 -2 -3 -1 -2 4 -1 -3 -3 2 -2 -1 -2 -1 -2 -1 4 -2 1 1 1 1 0 1 1 47 0 1 2 18 0 1 1 1 1 0 20 1 0.51 0.22 48 N -1 -1 5 3 -2 -1 0 -1 -1 -2 -3 -1 -2 -3 -2 0 2 -3 -2 -2 1 1 44 22 0 1 1 1 0 1 2 1 0 1 1 1 18 0 1 1 0.54 0.22 49 G -1 2 -1 -2 -3 -1 -2 5 -2 -3 -3 -1 -2 -3 -2 -1 -2 -2 -3 -3 1 18 1 1 0 1 1 65 0 1 2 1 0 1 1 1 1 0 1 1 0.74 0.22 50 A 4 -1 -2 -3 5 -1 -1 -1 -2 -2 -2 2 -2 -3 -2 0 -1 -3 -3 -1 62 0 0 0 17 0 0 0 0 0 0 21 0 0 0 0 0 0 0 0 0.56 0.27 51 L -2 -3 -4 -5 -2 -3 -4 -5 -4 1 5 -3 1 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.84 0.27 52 Q -2 5 -1 -2 -4 4 0 -3 -1 -4 -3 4 -2 -4 -2 -1 -2 -3 -3 -3 0 36 0 0 0 25 0 0 0 0 0 39 0 0 0 0 0 0 0 0 0.76 0.27 53 L -2 -3 -4 -4 -2 -3 -4 -4 -4 3 3 -3 3 -1 -4 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 21 31 0 13 0 0 0 0 0 0 35 0.54 0.27 54 N -2 -1 7 3 -4 -1 -1 -1 0 -4 -4 -1 -3 -4 -3 0 -1 -5 -3 -4 0 0 81 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.06 0.27 55 V 2 -3 -4 -4 -2 -3 -3 -3 -4 2 0 -3 0 -2 -3 -2 -1 -4 -2 5 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82 0.60 0.27 56 K 2 -1 -1 2 -3 0 2 -2 -2 -2 -3 1 -2 -3 -2 2 -1 -4 -3 0 21 0 0 17 0 0 19 0 0 0 0 12 0 0 0 18 0 0 0 13 0.30 0.27 57 L -2 -3 -4 -5 -2 -3 -4 -5 -3 1 5 -3 1 3 -4 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 81 0 0 19 0 0 0 0 0 0 0.73 0.27 58 P 1 -2 3 -1 -3 3 -1 -2 -2 -3 -3 -1 -2 -4 6 -1 -1 -4 -3 -3 18 0 19 0 0 21 0 0 0 0 0 0 0 0 42 0 0 0 0 0 0.86 0.27 59 G 2 -3 -2 -2 -3 -2 -2 5 -3 -4 -4 -2 -3 -4 3 -1 -2 -4 -4 -3 21 0 0 0 0 0 0 60 0 0 0 0 0 0 19 0 0 0 0 0 0.91 0.27 60 K -1 0 4 -1 -3 0 -1 -2 -1 -3 -3 3 -2 -4 -2 2 2 -4 -3 -3 0 0 36 0 0 0 0 0 0 0 0 25 0 0 0 21 18 0 0 0 0.53 0.27 61 S 3 -2 3 3 -2 -1 -1 2 -2 -3 -3 -1 -3 -4 -2 1 -1 -4 -3 -2 35 0 19 21 0 0 0 13 0 0 0 0 0 0 0 12 0 0 0 0 0.45 0.27 62 D -1 -2 0 5 -2 -1 0 2 -2 -2 -3 -1 -2 -3 -2 0 2 -3 -3 -2 1 1 1 43 0 1 1 21 0 1 2 1 0 1 1 1 22 0 1 1 0.49 0.22 63 W -3 -4 -5 -5 -3 -3 -4 -4 -3 -3 -2 -4 -2 3 -5 -4 -3 11 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 18 0 0 0 82 0 0 2.41 0.27 64 E -2 -1 0 5 -4 3 4 -3 -1 -4 -4 0 -3 -4 -2 -1 -2 -4 -3 -4 0 0 0 37 0 21 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0.84 0.27 65 E -2 -1 -1 1 -4 4 6 -3 -1 -4 -4 0 -2 -4 -2 -1 -2 -4 -3 -3 0 0 0 0 0 19 81 0 0 0 0 0 0 0 0 0 0 0 0 0 0.99 0.27 66 V -1 -3 -3 -4 -2 -3 -3 2 -3 1 2 -3 4 -1 -3 -2 -1 -3 -2 3 0 0 0 0 0 0 0 19 0 0 21 0 18 0 0 0 0 0 0 42 0.40 0.27 67 R -2 4 3 3 -4 0 0 -2 -1 -4 -4 4 -3 -4 -2 -1 -2 -4 -3 -3 0 25 18 19 0 0 0 0 0 0 0 38 0 0 0 0 0 0 0 0 0.62 0.27 68 V -1 -3 -4 -4 -2 -3 -4 -4 -4 3 2 -3 0 -1 -3 -3 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 18 21 0 0 0 0 0 0 0 0 61 0.61 0.27 69 A 2 -1 -2 -1 -3 0 4 -2 -2 -2 -2 2 -2 -3 -2 -1 -1 -4 -3 1 30 0 0 0 0 0 40 0 0 0 0 17 0 0 0 0 0 0 0 13 0.42 0.27 70 R -1 3 -1 -2 -3 -1 -1 2 -2 -2 1 2 -1 -3 -3 1 -1 -3 -3 -2 0 25 0 0 0 0 0 19 0 0 21 18 0 0 0 17 0 0 0 0 0.31 0.27 71 K -1 0 -1 -2 -3 3 0 -3 -2 -3 -3 4 -2 -4 3 -1 2 -4 -3 -2 0 0 0 0 0 19 0 0 0 0 0 43 0 0 17 0 21 0 0 0 0.59 0.27 72 F -3 -3 3 -2 -3 -3 -3 -3 -2 2 -1 -3 -1 6 -4 -2 -2 -1 1 -1 0 0 21 0 0 0 0 0 0 17 0 0 0 62 0 0 0 0 0 0 0.70 0.27 73 E -1 -2 0 5 -3 -1 2 -2 -2 -1 -3 -1 -2 -3 -2 1 -1 -4 -3 1 0 0 0 50 0 0 12 0 0 0 0 0 0 0 0 17 0 0 0 21 0.57 0.27 74 R -1 2 -1 0 -2 4 3 -1 0 -2 -2 0 -1 -2 -1 -1 -1 -2 -1 -2 3 14 2 2 1 35 19 3 1 2 3 2 1 1 2 3 2 0 1 2 0.37 0.17 75 L -3 -3 -4 -5 -2 -3 -4 -4 -3 0 4 -4 1 5 -4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 63 0 0 37 0 0 0 0 0 0 0.73 0.27 76 S 0 -2 -1 -2 -2 -1 -2 2 -2 -3 -3 -1 -2 -4 3 4 2 -4 -3 -2 0 0 0 0 0 0 0 21 0 0 0 0 0 0 13 47 19 0 0 0 0.55 0.27 77 E -1 -1 3 0 -4 0 3 2 -1 -2 -3 2 -2 -4 -2 -1 -1 -4 -3 0 0 0 21 0 0 0 29 19 0 0 0 18 0 0 0 0 0 0 0 13 0.38 0.27 78 C -2 -3 -3 -4 6 -3 -3 -4 -1 -1 -1 -3 -1 0 -3 -1 2 -1 5 2 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 17 0 37 21 0.63 0.27 79 E -1 0 3 0 -3 0 3 -2 -1 -4 -4 2 -3 -4 -2 3 0 -4 -3 -3 0 0 21 0 0 0 25 0 0 0 0 19 0 0 0 35 0 0 0 0 0.51 0.27 80 I -1 4 -1 -2 -3 -1 -2 -3 -2 2 -1 0 -1 -3 -3 2 2 -4 -2 -1 0 38 0 0 0 0 0 0 0 25 0 0 0 0 0 19 18 0 0 0 0.39 0.27 81 L -2 -3 -4 -4 -2 -3 -4 -4 -4 3 3 -3 1 -1 -4 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 17 43 0 0 0 0 0 0 0 0 40 0.58 0.27 82 E -1 0 -1 0 -4 1 5 -2 -1 -4 -4 3 -3 -4 -2 2 -1 -4 -3 -3 0 0 0 0 0 0 62 0 0 0 0 21 0 0 0 17 0 0 0 0 0.72 0.27 83 Y -2 -3 -3 -4 -3 -3 -3 -4 -1 0 -1 -3 -1 5 -4 -3 -2 0 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 43 21 0.84 0.27 84 D -2 -2 0 6 -4 -1 3 -2 -2 -3 -4 -1 -3 -4 -2 -1 2 -5 -3 -3 0 0 0 63 0 0 19 0 0 0 0 0 0 0 0 0 18 0 0 0 0.87 0.27 85 I -2 -3 -4 -4 -2 -3 -4 -4 -4 3 3 -3 4 -1 -4 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 25 35 0 19 0 0 0 0 0 0 21 0.55 0.27 86 Y -3 -3 -4 -4 -3 -3 -4 -4 0 -1 1 -3 -1 5 -4 -3 -3 1 6 -1 0 0 0 0 0 0 0 0 0 0 17 0 0 40 0 0 0 0 43 0 0.91 0.27 87 I -2 -4 -4 -4 -2 -4 -4 -5 -4 6 2 -4 1 -1 -4 -3 -2 -3 -2 2 0 0 0 0 0 0 0 0 0 83 17 0 0 0 0 0 0 0 0 0 0.76 0.27 88 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.35 0.27 89 N -2 3 4 2 -4 0 -1 -2 0 -4 -3 2 -3 -1 -3 -1 -2 -2 3 -3 0 17 30 13 0 0 0 0 0 0 0 21 0 0 0 0 0 0 19 0 0.50 0.27 90 V 2 -3 -2 2 -2 -2 -1 -2 -3 0 -1 -2 -1 -3 3 -1 -1 -4 -3 3 21 0 0 19 0 0 0 0 0 0 0 0 0 0 18 0 0 0 0 42 0.42 0.27 91 E 2 -2 -1 4 -3 0 4 -2 -2 -4 -4 -1 -3 -4 -2 -1 -2 -4 -3 -3 21 0 0 35 0 0 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0.70 0.27 92 G -1 0 3 -1 -3 0 -1 3 -1 -3 -3 4 -2 -3 -2 -1 -1 -3 -2 -3 1 1 22 1 0 1 1 26 0 1 2 38 0 1 1 1 1 0 1 1 0.44 0.22 93 L -1 -2 -2 -3 -2 3 -1 -3 -2 2 2 -2 0 -2 -3 1 -1 -3 -2 2 0 0 0 0 0 21 0 0 0 18 25 0 0 0 0 19 0 0 0 17 0.27 0.27 94 K -1 -1 3 -1 -3 3 0 -2 -1 -3 -3 2 -2 -4 -2 3 2 -4 -3 -3 0 0 17 0 0 19 0 0 0 0 0 12 0 0 0 39 13 0 0 0 0.47 0.27 95 G 2 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -3 21 0 0 0 0 0 0 79 0 0 0 0 0 0 0 0 0 0 0 0 1.08 0.27 96 R 1 3 -1 -2 -3 -1 -1 2 -2 -3 -3 2 -2 -4 -2 0 2 -4 -3 -2 17 25 0 0 0 0 0 19 0 0 0 18 0 0 0 0 21 0 0 0 0.39 0.27 97 L -2 -3 -4 -4 -2 -3 -4 -5 -3 3 4 -4 1 3 -4 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 21 60 0 0 19 0 0 0 0 0 0 0.62 0.27 98 R 1 6 -2 -3 -3 0 -1 -3 -1 -2 -2 1 3 -3 -3 -1 -2 -3 -2 -2 19 63 0 0 0 0 0 0 0 0 0 0 18 0 0 0 0 0 0 0 0.66 0.27 99 P -1 -3 -3 -3 -3 -2 -3 2 -2 -2 -2 -2 -2 -1 6 -2 -2 -2 3 1 0 0 0 0 0 0 0 21 0 0 0 0 0 0 42 0 0 0 19 18 0.80 0.27 100 Y 1 -1 -3 -3 -3 -2 -2 -3 -1 2 -1 2 -1 1 -3 -2 -2 0 6 -1 18 0 0 0 0 0 0 0 0 21 0 19 0 0 0 0 0 0 42 0 0.45 0.27 101 A 2 -3 -2 -3 -2 -2 -2 -2 -3 2 -1 -2 -1 -2 -2 1 -1 -4 -2 3 25 0 0 0 0 0 0 0 0 17 0 0 0 0 0 18 0 0 0 40 0.36 0.27 102 V 3 -2 -2 -3 -2 3 -1 -2 -2 0 -1 -1 -1 -3 -2 -1 -1 -3 -2 3 35 0 0 0 0 21 0 0 0 0 0 0 0 0 0 0 0 0 0 44 0.38 0.27 103 L -2 -3 -4 -4 -2 -3 -4 -5 -4 4 4 -3 1 -1 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 37 63 0 0 0 0 0 0 0 0 0 0.68 0.27 104 N -2 -2 6 3 -4 -1 -1 -2 -1 -4 -4 -1 -3 -4 4 -1 -1 -5 -3 -4 0 0 61 18 0 0 0 0 0 0 0 0 0 0 21 0 0 0 0 0 0.93 0.27 105 P -2 -2 3 3 -4 -2 -1 -2 -2 -4 -4 -2 -3 -4 7 -1 -2 -5 -4 -3 0 0 18 19 0 0 0 0 0 0 0 0 0 0 63 0 0 0 0 0 1.39 0.27 106 G -1 -3 -1 3 -4 -2 -2 5 -3 -4 -4 -2 -4 -4 3 -1 -2 -4 -4 -4 0 0 0 21 0 0 0 61 0 0 0 0 0 0 18 0 0 0 0 0 0.94 0.27 107 W -3 -4 -5 -5 -3 -3 -4 -3 -3 -3 -2 -4 -2 0 -5 -4 -3 12 2 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2.95 0.27 108 V -1 -1 -2 -2 -2 -1 -1 -2 -2 2 -1 2 -1 -2 -2 -1 2 -3 -2 3 1 1 1 1 0 1 1 1 0 18 2 20 0 1 1 1 22 0 1 26 0.23 0.22 109 K -2 1 -1 -1 -4 3 3 -3 -1 -4 -3 5 -2 -4 -2 -1 -1 -4 -3 -3 0 0 0 0 0 18 19 0 0 0 0 63 0 0 0 0 0 0 0 0 0.73 0.27 110 I -2 -3 -4 -4 -2 -3 -4 -5 -2 5 2 -3 0 0 -4 -3 -2 -1 4 1 0 0 0 0 0 0 0 0 0 60 19 0 0 0 0 0 0 0 21 0 0.60 0.27 111 G -1 -3 -2 -2 -3 -3 -3 6 -3 1 -3 -3 -2 -3 -3 -1 -2 -3 -4 -2 0 0 0 0 0 0 0 82 0 18 0 0 0 0 0 0 0 0 0 0 1.02 0.27 112 L -1 -1 -2 -3 -2 -1 -2 -3 -3 0 2 2 4 -2 -3 1 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 0 25 18 21 0 0 19 0 0 0 17 0.27 0.27 113 D -2 -2 0 6 -4 -1 3 -2 -2 -3 -4 -1 -3 -4 -2 -1 2 -4 -3 -3 0 0 0 60 0 0 19 0 0 0 0 0 0 0 0 0 21 0 0 0 0.83 0.27 114 M -2 -2 -2 -3 -3 2 -2 -3 -2 -1 0 -2 4 5 -3 -1 2 -1 0 -1 0 0 0 0 0 17 0 0 0 0 0 0 25 37 0 0 21 0 0 0 0.47 0.27 115 N -1 -1 4 -1 -2 -1 -1 -2 -1 -2 -2 -1 -1 -1 -2 0 4 -1 3 -1 1 1 26 1 0 1 1 1 0 1 2 1 0 1 1 1 40 0 17 1 0.40 0.22 116 N 1 -1 5 0 -3 0 2 -2 4 -4 -4 -1 -3 -3 -2 0 -1 -4 -2 -3 18 0 44 0 0 0 21 0 17 0 0 0 0 0 0 0 0 0 0 0 0.60 0.27 117 A 1 -1 -2 -3 -2 -2 -2 -3 -3 4 0 2 0 -2 -3 -1 1 -4 -2 2 12 0 0 0 0 0 0 0 0 37 0 21 0 0 0 0 13 0 0 17 0.30 0.27 118 N -2 -1 6 0 -3 -1 -1 -1 -1 -3 -4 -1 -3 -4 -2 2 2 -4 -3 -3 0 0 68 0 0 0 0 0 0 0 0 0 0 0 0 13 19 0 0 0 0.82 0.27 119 V 1 -3 -3 -4 -2 -3 -3 -3 -2 2 2 -3 0 0 -3 -2 -1 -2 3 3 19 0 0 0 0 0 0 0 0 13 21 0 0 0 0 0 0 0 18 29 0.35 0.27 120 E -1 -1 5 2 -3 0 2 -2 -1 -4 -4 2 -3 -4 -2 2 -1 -4 -3 -3 0 0 36 13 0 0 12 0 0 0 0 18 0 0 0 21 0 0 0 0 0.55 0.27 121 S 2 -2 0 5 -3 -1 0 -1 -2 -3 -4 -1 -3 -4 -2 2 -1 -4 -3 -3 19 0 0 56 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0.71 0.27 122 A 1 -2 -2 -3 -3 -2 -2 3 -3 -1 2 2 0 -2 -3 -1 -2 -3 -3 -1 12 0 0 0 0 0 0 32 0 0 38 18 0 0 0 0 0 0 0 0 0.34 0.27 123 E -2 0 3 0 -3 3 3 -2 -1 -3 -3 2 -2 -4 -2 0 2 -4 -3 -3 0 0 18 0 0 21 25 0 0 0 0 19 0 0 0 0 17 0 0 0 0.50 0.27 124 I 2 -1 -1 -2 -2 -1 -1 -2 -2 1 0 2 -1 -2 -2 2 2 -3 -2 -1 18 0 0 0 0 0 0 0 0 12 13 19 0 0 0 21 17 0 0 0 0.22 0.27 125 I -1 -4 -4 -4 -2 -3 -4 -4 -4 4 0 -3 0 -1 -3 -3 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 30 0 0 0 0 0 0 0 0 0 70 0.70 0.27 126 T -1 -1 -1 -2 -2 3 -1 -3 -2 -1 -2 2 -1 -3 -2 1 3 -3 -2 2 0 0 0 0 0 18 0 0 0 0 0 19 0 0 0 13 29 0 0 21 0.33 0.27 127 F -2 -4 -4 -4 -2 -4 -4 -5 -4 5 1 -4 0 4 -4 -3 -2 -2 0 1 0 0 0 0 0 0 0 0 0 75 0 0 0 25 0 0 0 0 0 0 0.72 0.27 128 G -2 -2 5 4 -4 -1 0 1 4 -4 -4 -1 -3 -4 -3 -1 -2 -4 -2 -4 0 0 37 34 0 0 0 12 17 0 0 0 0 0 0 0 0 0 0 0 0.74 0.27 129 G -1 -2 3 -1 -4 -1 2 5 -2 -5 -4 -1 -3 -4 -3 -1 -2 -4 -4 -4 0 0 17 0 0 0 21 62 0 0 0 0 0 0 0 0 0 0 0 0 0.84 0.27 130 K -2 1 -1 -1 -4 3 3 -3 -1 -4 -3 5 -2 -4 -2 -1 -1 -4 -3 -3 0 0 0 0 0 17 21 0 0 0 0 62 0 0 0 0 0 0 0 0 0.73 0.27 131 E -2 -1 0 4 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17 0.40 0.27 140 E -2 -1 3 5 -4 0 4 -2 -1 -4 -4 -1 -3 -4 -2 -1 -2 -4 -3 -4 0 0 18 40 0 0 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0.85 0.27 141 F -3 -3 -4 -4 -3 -3 -4 -4 -1 -1 2 -4 0 6 -4 -3 -3 0 4 -1 0 0 0 0 0 0 0 0 0 0 21 0 0 61 0 0 0 0 18 0 0.90 0.27 142 D -2 -1 4 4 -3 0 3 -1 -1 -3 -3 -1 -2 -3 -2 0 -1 -3 -2 -3 1 1 36 26 0 1 22 1 0 1 2 1 0 1 1 1 1 0 1 1 0.57 0.22 143 R 3 4 -2 -3 -2 -1 -1 -2 -2 -1 -2 2 -2 -3 -2 -1 -1 -4 -2 1 38 31 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 18 0.40 0.27 144 T -1 -2 3 -1 -2 -1 -2 -2 -2 -2 -2 -1 3 -3 -2 2 4 -3 -2 -1 0 0 18 0 0 0 0 0 0 0 0 0 17 0 0 21 44 0 0 0 0.48 0.27 145 A 3 -1 -2 -2 -2 -1 -1 -2 -2 -3 -3 2 -2 -4 5 0 2 -4 -3 -2 33 0 0 0 0 0 0 0 0 0 0 19 0 0 29 0 18 0 0 0 0.62 0.27 146 G 2 0 3 -1 -3 -1 -1 3 -2 -4 -3 4 -3 -4 -2 0 -1 -4 -3 -3 21 0 17 0 0 0 0 25 0 0 0 37 0 0 0 0 0 0 0 0 0.47 0.27 147 V 3 2 -3 -3 -2 -2 -2 -2 -3 0 -1 -1 -1 -2 -2 -1 -1 -4 -2 3 39 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42 0.38 0.27 148 K 1 -1 5 0 -3 -1 -1 -1 -1 -3 -3 1 -2 -4 -2 0 2 -4 -3 -2 19 0 47 0 0 0 0 0 0 0 0 12 0 0 0 0 21 0 0 0 0.54 0.27 149 E -1 -1 -1 -1 -3 3 4 2 -1 -2 -3 -1 -2 -4 -2 -1 -2 -3 -3 1 0 0 0 0 0 19 42 21 0 0 0 0 0 0 0 0 0 0 0 18 0.47 0.27 150 L -2 -3 -4 -5 -2 -3 -4 -5 -4 1 5 -3 1 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.84 0.27 151 H 2 -2 -2 -3 -2 -2 -2 -3 5 0 -1 -2 -1 3 -3 -2 -1 -2 0 3 21 0 0 0 0 0 0 0 25 0 0 0 0 17 0 0 0 0 0 37 0.40 0.27 152 I -2 -3 -4 -4 -2 -3 -4 -5 -3 3 4 -4 1 3 -4 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 25 56 0 0 19 0 0 0 0 0 0 0.61 0.27 153 G -1 2 3 -1 -3 3 -1 3 -1 -4 -4 0 -2 -4 -2 2 -1 -4 -3 -3 0 18 17 0 0 19 0 25 0 0 0 0 0 0 0 21 0 0 0 0 0.47 0.27 154 V -2 -4 -4 -4 -2 -3 -4 -4 -4 4 2 -4 0 3 -4 -3 -2 -2 -1 3 0 0 0 0 0 0 0 0 0 35 21 0 0 19 0 0 0 0 0 25 0.53 0.27 155 V 3 -3 -3 -3 -1 -2 -3 -2 -3 1 -1 -2 -1 -2 -3 -1 -1 -4 -2 4 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63 0.51 0.27 156 G -1 -3 -1 -2 -3 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.43 0.27 157 D -2 -1 5 4 -3 3 0 -2 -1 -4 -4 -1 -3 -4 -2 2 -1 -4 -3 -3 0 0 38 25 0 19 0 0 0 0 0 0 0 0 0 18 0 0 0 0 0.65 0.27 158 H 1 -1 3 -2 -3 -1 -1 -2 5 -3 -3 2 -2 -1 -3 -1 -2 -2 4 -3 21 0 19 0 0 0 0 0 25 0 0 17 0 0 0 0 0 0 18 0 0.47 0.27 159 L -1 -3 -3 -3 -2 -3 -3 -3 -3 3 3 -3 0 -1 -3 1 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 21 42 0 0 0 0 19 0 0 0 18 0.39 0.27 160 R 1 2 3 3 -3 0 2 -2 -1 -4 -4 2 -3 -4 -2 -1 -1 -4 -3 -3 17 12 19 21 0 0 13 0 0 0 0 18 0 0 0 0 0 0 0 0 0.43 0.27 161 Y -3 -3 -3 -4 -3 -3 -3 -4 1 -2 -1 -3 -2 4 -4 -3 -3 1 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 21 0 0 0 0 79 0 1.26 0.27 162 D -1 0 0 3 -3 0 0 -2 -2 -3 -3 3 -2 -4 -2 0 4 -4 -3 -2 0 0 0 25 0 0 0 0 0 0 0 36 0 0 0 0 39 0 0 0 0.53 0.27 163 G -1 -3 -1 -2 -3 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.43 0.27 164 P 2 -3 -3 -2 -3 -2 -2 -2 -3 -3 -3 -2 -3 -4 8 -1 -2 -4 -4 -3 21 0 0 0 0 0 0 0 0 0 0 0 0 0 79 0 0 0 0 0 1.73 0.27 165 I -2 -4 -4 -4 -2 -4 -4 -5 -4 6 1 -4 0 -1 -4 -3 -2 -3 -2 2 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.86 0.27 166 F -3 -3 -3 -4 -3 -3 -3 -4 1 -2 -1 -3 -2 5 -4 -3 -3 1 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 75 0 1.23 0.27 167 I -2 -4 -4 -4 -2 -3 -4 -5 -4 5 2 -3 1 -1 -4 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 60 19 0 0 0 0 0 0 0 0 21 0.65 0.27 168 D -3 -2 1 7 -4 -1 1 -2 -2 -4 -5 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.38 0.27 169 N -2 -1 7 1 -4 -1 -1 -1 0 -4 -4 -1 -3 -4 -3 0 -1 -5 -3 -4 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.22 0.27 170 V -1 -4 -4 -4 -2 -3 -4 -4 -4 3 0 -3 0 -1 -3 -3 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 21 0 0 0 0 0 0 0 0 0 79 0.71 0.27 171 R -2 5 -1 -2 -4 3 0 -3 -1 -3 -3 3 -2 -4 -2 -1 2 -3 -2 -3 0 44 0 0 0 21 0 0 0 0 0 18 0 0 0 0 17 0 0 0 0.65 0.27 172 L -2 -3 -4 -4 -2 -3 -4 -5 -4 3 5 -3 1 0 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 19 81 0 0 0 0 0 0 0 0 0 0.73 0.27 173 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -1 -1 -3 -1 5 -4 -2 -2 2 6 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 0 0 60 0 0.86 0.08 174 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.65 0.08 175 R -1 4 -1 -1 -4 1 0 -2 -1 -3 -3 5 -2 -3 -2 -1 -1 -3 -2 -3 0 30 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0.63 0.08 176 T 1 -1 0 -1 -1 0 -1 -1 -1 -2 -2 -1 -1 -2 -1 3 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 50 0 0 0 0.41 0.02 177 G 0 -2 0 -1 -2 -2 -2 5 -2 -4 -4 -1 -3 -3 -2 0 -2 -2 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 178 G 0 -2 0 -1 -2 -2 -2 5 -2 -4 -4 -1 -3 -3 -2 0 -2 -2 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 179 M -1 -1 -2 -3 -1 0 -2 -3 -2 1 2 -1 5 0 -2 -1 -1 -1 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 K Lambda Standard Ungapped 0.1388 0.3176 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1611 0.3172 PSI Gapped 0.0493 0.2670